Recent legislative and regulatory events, including the potential rescheduling from Schedule I to Schedule III and the SAFER Banking Act, are leading to a dramatic shift in the cannabis industry, with a particular impact on cannabinoid research.

Israeli researcher finds that a combination of THC, CBC, and CBG shows anticancer activity against ovarian cancer cells. The cannabinoids also worked well with niraparib—a common chemotherapy drug—but not at all with gemcitabine, another chemotherapy drug.

California state law requires cancer centers to allow patients with terminal disease to use cannabis, contradicting federal law. That has left some oncology nurses uncertain about their roles and responsibilities, but a survey-based pilot study suggests most will be comfortable overseeing patient self-administration of cannabis in clinical settings, and that they will see palliative benefits…

Psychedelic therapies could someday help treat a range of conditions ranging from alcoholism to Alzheimer’s disease and from long COVID to chronic Lyme disease.

A systematic literature review examining the use of cannabidiol (CBD) for a variety of medical conditions shows that CBD is well-tolerated in adults and children, with few adverse events (AEs). The literature review, published in Current Neuropharmacology, noted that more research is needed around interactions with other medications. “Compelling evidence from preclinical and clinical studies…

With demand for hemp extracts growing rapidly, researcher Kevin Spelman, PhD, MCPP, decided to conduct a real-world evidence study examining the safety profile of full-spectrum CBD products.

Patients that experience seizure clusters secondary to conditions such as Lennox-Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex could benefit from the concomitant use of cannabinol (CBD) and diazepam nasal spray, as the former does not significantly impact the latter’s safety or efficacy, according to a recently published study in Epilepsy & Behavior. Cannabinol, in the form of…

Findings from a study recently published in Proceedings of the National Academy of Sciences of the United States of America illustrates how cannabinoid signaling may regulate the stress response in the brain. In a series of experiments performed in in vitro and ex vivo models, researchers from Vanderbilt University and Northwestern University, found that cannabinoid signaling…

(HealthDay News) — Medical cannabis provides pain relief and reduces opioid use in patients with cancer, according to a study published in BMJ Supportive & Palliative Care. Researchers examined the safety and effectiveness of medical cannabis in reducing pain and concurrent medications in 358 patients with cancer who were part of the Quebec Cannabis Registry. At…

The US Drug Enforcement Administration (DEA) decided to fire “outstanding” special agent Anthony Armour after he tested positive for tetrahydrocannabinol (THC) due to consuming a cannabidiol (CBD) product that he says he thought was legal hemp. Mr. Armour had sought to use CBD for pain relief instead of prescription opioids and had been with the DEA…