Patient Safety

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Patient Perceptions on the Efficacy and Safety of Cannabidiol Products and the Role of the Pharmacist: A Cross-Sectional Study

Although CBD products are generally recognized as effective and safe, potential safety concerns exist that may go unaddressed. This study demonstrates that pharmacists, who are one of the most accessible health care professionals, can serve as a valuable resource to patients regarding the safe use of CBD products.

Liposomal Cannabidiol Delivery: A Pilot Study

Introduction Although oral cannabidiol (CBD) formulations are increasingly popular, studies show that oral CBD has a much lower bioavailability than inhaled CBD.1 This study was designed to compare the bioavailability of 2 different preparations of oral CBD, with and without a liposomal delivery system. Puffin Hemp has a patent-pending liposome manufacturing technology that is used…

Patient Safety News

CBD Well-Tolerated, Few Adverse Events  
A systematic literature review examining the use of cannabidiol (CBD) for a variety of medical conditions shows that CBD is well-tolerated in adults and children, with few adverse events (AEs). The literature review, published in Current Neuropharmacology, noted that more research is needed around interactions with other medications. “Compelling evidence from preclinical and clinical studies…
CBD Safety Profile: Real-World Evidence Study Shows Compelling Results for Full-Spectrum CBD
With demand for hemp extracts growing rapidly, researcher Kevin Spelman, PhD, MCPP, decided to conduct a real-world evidence study examining the safety profile of full-spectrum CBD products.
Reliable Cannabis Breathalyzer Remains Elusive for Researchers
A reliable breathalyzer to detect recent cannabis use and impairment would be a critical tool for law enforcement officers, however, it does not currently exist according to a study published in the Journal of Breath Research.1 The researchers in the study, a collaboration between the National Institute of Standards and Technology (NIST) and the University…
Pediatric Hospitals See Increase in Cannabis Intoxication From THC Gummies
Stony Brook Children’s Hospital in Long Island, New York, is reporting an increase in young children with cannabis intoxication in its emergency department.1 Similarly, a retrospective review, published in Pediatrics, of 80 children aged <6 years in a Colorado urban pediatric hospital network confirms an increase in exposure to cannabis edibles.2 Children can mistake the…
Evidence Mounts for Low and Ultra-Low Doses of Cannabinoid-Based Therapy 
Dustin Sulak, DO, considers anything less than 0.5 mg per day to be an ultra-low dose of cannabinoids for an adult.
Oral CBD Not Associated With Elevated Liver Enzymes, Low Testosterone in Men
A new study shows that men who self-dose oral, daily cannabidiol (CBD) for at least 30 days do not experience elevated liver test (LT) results, low total testosterone (TT) levels, or daytime drowsiness (DD). The study, published in Medical Cannabis and Cannabinoids, also found decreased DD and a lower prevalence of low TT in older…